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Combiflash RF系列快速制备色谱仪

产品详细信息

中压快速制备色谱是用于分离、提纯化合物,能够快速得到大量的纯度较高的化合物。

应用范围:有机合成、药物化学、生物化学、天然产物的分离

目前科研过程中要得到纯度高、大量的化合物,才能进行后续的科研工作、所以前期样品分离的工作量非常多而杂,使用快速制备色谱是一个有效的解决方案,能够得到较多重量的化合物,可以进行后期的结构鉴定、理化常数的测量、筛选等工作。

中压快速制备色谱能够快速、准确的按照用户要求的条件进行分离纯化工作。

产品特点:

  • 产品设计紧凑、体积小巧
  • 多型号可选:Rf150, Rf200, Rf200i, Rf 4X
  • 仪器由泵系统、检测系统、收集系统、控制系统组成
  • 无需计算机,通过触摸屏操控
  • 通过触屏点击、拖拽实现整个分离方法的开发
  • 分离结束后色码标示各馏分位置

可选型号:

Rf150

150psi压力, 100ml/min流速

Rf200

200psi压力, 200ml/min流速

Rf200i

一体的UV/UV-vis/ELSD 检测器

Rf 4x

同时过高达4个柱子

Torrent

放大型,流速可达1L/min,样品量可达300g

CombiFlash® Rf 200

Making flash chromatography easy 

Teledyne Isco advances automated chromatography again with the CombiFlash Rf 200 system. The CombiFlash® Rf 200 uses RFID (Radio Frequency Identification) technology to automate setting the parameters for purification runs and fraction collection.

The CombiFlash® Rf 200 has built-in solvent and waste management that prevent columns from drying, and messy waste overfills. A new automated valve lets you load samples and walk away - and it's self-cleaning to wash away materials that can contaminate the next run.

The CombiFlash® Rf 200 improves your productivity whether you separate synthetic compounds, natural products, peptides, polymers, or other chemical separations.Standard Features

  • Space saving design is smaller than other flash chromatography systems on the market, freeing scarce hood space for other uses.
  • Solvent and waste management prevents columns from drying and waste containers from hazardous overflows.
  • Large touch screen 10.5 inch (26.7 cm) puts the most used controls on a single, easy to read display.
  • Large fraction capacity allows longer runs without changing racks. You don't need to divert time from other activities to watch your purification.
  • RFID (Radio Frequency Identification) identifies columns and loads the appropriate method for the best separation. With reusable bonded-phase columns, the system tracks the number of runs on the column as well as the last solvent used, so you know whether you need to flush the column.
  • RFID identification of fraction collection racks sets the maximum fraction size to prevent overflows.
  • Injection valve features wide bore, straight plumbing, and self-cleaning to prevent clogs that cause down-time.
  • No waiting to access data - networking allows lets you connect to the CombiFlash® Rf 200 to monitor and remotely control your experiment, analyze data, and print to network printers.
  • Rapid column air purge prevents solvent from being discarded with the used column. It is better for the environment, safer in the lab, and eliminates messy column removal.
  • TLC Rf to Gradient calculator determines optimal separation parameters while minimizing run time.
  • Easy scale-up with built-in method-scaling means you won’t need to re-develop your method. You save time when you increase reaction size. You can even scale up to a 3 kg column run on a CombiFlash Torrent.
  • Back pressures to 200 psi for improved separations.
  • May be ordered in either variable UV 200 - 360 nm, variable UV-Vis 200 - 780 nm configurations
  • One-year parts and labor warranty.

Applications

  • Organic synthesis purification
  • Agricultural chemicals
  • Medicinal chemistry
  • Peptides and polymers

Options and Accessories

  • 13 x 100 mm tube racks, qty 2 (108 tubes/rack)
  • 16 x 125 mm tube racks, qty 2 (75 tubes/rack)
  • 16 x 150 mm tube racks, qty 2 (75 tubes/rack)
  • 18 x 150 mm tube racks, qty 2 (70 tubes/rack)
  • 18 x 180 mm tube racks, qty 2 (70 tubes/rack)
  • 25 x 150 mm tube racks, qty 2 (30 tubes/rack)
  • 480 mL French square bottle, qty 1 rack for 12 bottles
  • 20 mL (28 x 61 mm) scintillation vial tube racks, qty 2 (27 vials/rack)
  • 40 mL (28 x 95 mm) scintillation vial tube racks, qty 2 (30 vials/rack)
  • Adjustable Solid Load Cartridge Caps (SLCC), 5 gram, 25 gram, and 65 gram
  • RediSep Rf prepacked columns
  • Sample load prepacked, silica gel cartridges
  • Sample load, empty cartridges

Parts and Supplies

Specifications

CombiFlash Rf 200
Controller: 10.5 inch touchscreen (26.7 cm), or external web browser via ethernet. Data and current run can be accessed by up to 10 remote computers. Front panel USB port to save data and transfer files.
PeakTrak software for: One-screen method development; Real-time control - change method parameters during a run without pausing; Converting Rf values into solvent gradients; Method scaling -transfer method from one size column to another, from 4 g to 330 g; Converting methods to 3000 g columns on CombiFlash Torrent; Color-coded fraction identification.
Programmable gradients: Linear and/or step gradients. Change profiles anytime during run, using "Click and drag" gradients. Pause gradient for isocratic hold.
Pumping system: Positive displacement pumps. 5-200 mL/min. 0-200 psi (when used with RediSep Rf columns)
Gradients: Four solvent, binary; Accuracy: < 1% full scale
Column sizes: 4 g to 330 g.
Fraction collection: Internal fraction collector capacity- 13x100 mm tubes - 216, 16x125/150 mm tubes - 150, 18x150/180 mm tubes - 140, 25x150 mm tubes - 60, 40 mL scintillation vials - 60, 20 mL scintillation vials - 54, 480 mL bottles - 12.
Fraction Size: Determined by peak cutting and by user-defined maximum tube volume
Sample injection: Autoinject with 6-position motor powered sample loading valve; self-cleans at end of run; solid or liquid injection
Detection (685230006 systems): Software selectable UV variable dual-wavelength, 200-360 ; slope and threshold peak detection; detector range- 0.2-3.0 AUFS; determination of peak purity by 2 wavelength ratio.
Detection (685230008 systems): Software selectable UV variable dual-wavelength, 200 - 780 nm; slope and threshold peak detection; detector range- 0.2-3.0 AUFS; determination of peak purity by 2 wavelength ratio.
Safety: Static dissipating tubing, vapor sensor, and column air purge.
Sample security: Auto-run extension at end of run, and over pressure sensor.
Solvent management: Four solvent and one waste fluid level monitoring
Dimensions (W x D x H): 14.1 x 17 x 24 inches, (35.8 x 43.2 x 61.0 cm)
Weight: 54 lbs. (24.5 kg)
Certifications: CE and CSA
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